Natural Antioxidants for Cats

Understand the food sources, the difference between powders and extracts, and the feline research behind a thoughtful daily choice.

By La Petite Labs Editorial 19 min read

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Contents

Natural antioxidants for cats include nutrients in food, compounds in plant ingredients and protective substances the body makes itself. Vitamin E contributes antioxidant protection; dietary protein supplies amino acids used to make glutathione. Berries and other botanical ingredients bring a different set of compounds, whose effects depend on the preparation and amount. 1 4 6

You can understand those ingredients without turning dinner into a collection of home remedies. Hollywood Elixir® brings food powders, selected extracts and nutrients together in its full 17-active NAD+ healthy-aging formula, made for daily cellular energy and antioxidant nutrition alongside a complete diet. Here is what the sources and actual cat studies tell us about that choice. 10

  • Antioxidant nutrition includes dietary vitamin E, materials for the body’s own glutathione and compounds in plant ingredients.
  • “Natural” describes sources and permitted processing; it does not make a powder, an extract and a whole food equivalent.
  • Cats require preformed vitamin A and normally make vitamin C. A complete feline diet remains the foundation.
  • Specific berry-containing and botanical cat foods produced measured blood changes. Those results belong to the tested formulations.
  • Hollywood Elixir combines its full 17 actives for cellular energy and antioxidant healthy-aging nutrition, including precisely declared powders and extracts.
  • Choose the actual portion and a routine the cat accepts; do not judge antioxidant status from appetite, coat or energy alone.

Where does natural antioxidant nutrition begin?

It begins with the meal. A complete cat food supplies essential nutrients, including antioxidant vitamin E, while protein contributes the amino acids a cat uses to build its own protective molecules. Food ingredients and added nutrients can both serve that nutritional purpose. 1 3 4

Plant ingredients add another possibility. Blueberries contain polyphenols, a broad family of plant compounds studied for antioxidant activity. Their presence on a label tells you the source; it does not tell you the amount of every compound or what an individual cat will experience. 9

A useful approach to natural nutrition for cats starts with adequate food and then considers the particular addition. It need not turn food choice into a contest over the fewest ingredients.

Woman kneeling with two long-haired tabby cats while holding a Hollywood Elixir box beside a food bowl

What does “natural” mean on a pet-food label?

AAFCO’s definition allows ingredients from plant, animal or mined sources and permits processes including heating, extraction, hydrolysis and fermentation. A natural ingredient can therefore be processed. The term does not, by itself, establish that an ingredient is safer or more effective. 2

That distinction helps when comparing a fruit powder with an extract. The relevant questions are what the preparation contains and why it is included. A whole product’s “all-natural” claim also has different requirements from a claim about one ingredient. A formula can combine food powders with selected nutrient forms without being an all-natural product.

Woman exercising beside a tabby cat, with a Hollywood Elixir box and food bowl on a small table

How does antioxidant nutrition fit a carnivorous cat?

Cats require preformed vitamin A; pumpkin or other beta-carotene-rich plants cannot supply that requirement through the conversion humans use. Cats normally make vitamin C in the liver, while vitamin E is an essential dietary antioxidant. These are different nutritional jobs. 1

Animal-source ingredients remain important to a cat’s food. At the same time, being a carnivore does not tell us that every plant ingredient is inactive: feline feeding studies can answer that more specific question. The studies below concern carefully formulated foods or defined supplements, not replacing a meat-based meal with produce.

Our guides to vitamin E for cats and senior cat food explore those separate decisions.

Orange-and-white cat reaching toward a woman holding a Hollywood Elixir box while sitting in a chair

Protein also feeds a cat’s own antioxidant system

Cells assemble glutathione from glutamate, cysteine and glycine, three amino acids. Protein nutrition supplies building materials for this work, which also uses cellular energy. Glutathione is therefore part of the connection between a cat’s meal and defenses made inside the body. 4

Glutathione peroxidase enzymes use glutathione to help deal with peroxides, reactive molecules that can damage cells when not controlled. This is useful normal chemistry, not evidence that a cat needs a particular supplement simply because it is older. 5

The broader explanation of oxidative stress in cats covers what happens when damaging oxidation outpaces protective processes.

Gray-haired man holding a Hollywood Elixir box while two cats rest beside him in an armchair

Blueberries: a food, a powder and an extract supply different amounts

A fresh blueberry contains water and a mixture of food components. Drying removes water; an extract is produced to select or concentrate particular constituents. Those changes affect what a measured amount supplies. The word “blueberry” alone cannot make the preparations equivalent.

Hollywood Elixir declares 50 mg of Blueberry Fruit Powder per full sachet. That is the amount of powder, not a declared 50 mg of polyphenols or anthocyanins. Its resveratrol and quercetin ingredients, by contrast, specify particular forms and concentrations on the full panel. 10

The fruit powder contributes a mixture of fruit components; a standardized extract specifies the concentration of selected constituents. This is why the form belongs beside the amount when comparing ingredients.

Protein supplies amino acids cats use to make glutathione, one of their own antioxidant defenses.

What happened in the berry-containing cat-food study?

A 2022 conference report studied 30 healthy adult cats in a randomized crossover trial. Each treatment period lasted 28 days, separated by a 14-day washout. Researchers compared a maintenance diet with the diet supplemented by an antioxidant-containing kibble blend that included blueberries, cranberries and other ingredients. 6

Cats eating the test diet had lower blood measurements of advanced glycation end-products and malondialdehyde, markers associated with oxidative damage, and lower C-reactive protein. Food intake and body weight were similar between treatments.

This is a positive feline finding for a particular food blend. It does not isolate blueberries or establish the effect of fruit added at home. All authors were affiliated with Blue Buffalo, and the report was a conference abstract rather than a full-length trial paper.

Tabby cat looking up at a Hollywood Elixir sachet held above it, with the product box on a small table

Can botanical ingredients affect cats despite their carnivory?

A 2021 study assigned 48 healthy adult cats to four groups for 84 days. Their complete foods differed in a blend of green tea, fenugreek and tulsi extracts, additional arachidonic acid from chicken liver, or both. 7

The botanical-only group had lower circulating cholesterol and triglycerides and ate less food. The group receiving both the botanicals and additional arachidonic acid had reductions in several measured inflammatory signaling proteins. Those were different findings from different formulations.

The study shows that cats can respond to specific plant-containing foods. It did not test disease treatment, and those three botanicals are not Hollywood Elixir ingredients. Hill’s funded the work; the authors were current or former employees. The useful lesson is about the complete preparation, not a recipe for adding tea or herbs to dinner.

Hand gently petting an orange-and-white cat beside a food bowl and Hollywood Elixir box

Astaxanthin has direct feline research, with a precise limit

Astaxanthin is a carotenoid antioxidant. In a 2011 study, young female cats received 0, 1, 5 or 10 mg daily for 12 weeks. Several immune measurements increased, including natural-killer-cell activity and antibody concentrations; not every measured immune-cell population changed. 8

These were immune assays, not a demonstration of fewer infections or longer lives. Hollywood Elixir’s label reads Astaxanthin 2% (natural), 2 mg per full sachet. That describes a 2% preparation, not 2 mg of pure astaxanthin, so it should not be presented as the same dose used in that study. 10

For the wider topic, see immune health for cats.

Man holding a Hollywood Elixir box beside a black cat, an orange tabby and a food bowl

Why a plant name cannot tell the whole story

A 2025 investigation tested 40 bags of dog and cat kibble listing blueberries, including 18 cat foods. It measured quercetin and selected other phenolic compounds and found low concentrations of the measured compounds. This was a food-composition study, not a trial of health outcomes in cats. 9

It helps explain why an ingredient name cannot stand in for a compositional measurement. It does not prove that the foods had no nutritional benefit, and the tested panel was not an anthocyanin assay.

For a supplement, use the same practical distinction: the declared ingredient, its form and its amount describe what is supplied. The purpose of the whole formula explains why you might choose it.

Why Hollywood Elixir combines more than plant antioxidants

The appeal of a botanical ingredient is easier to understand when its place in the formula is clear. Hollywood Elixir combines blueberry and spirulina powders with selected resveratrol, quercetin and astaxanthin preparations. It also includes glutathione, vitamins and ingredients connected with the way cells use food energy. 10

That is the purpose of its full 17-active NAD+ system: daily nutrition for cellular energy, antioxidant defense and healthy aging. It is a prepared choice for an owner who wants those related functions considered together, instead of assembling separate extracts.

The studies above tested their own foods or ingredients, not the finished Hollywood Elixir formula. They do not establish that it will reproduce those results or extend a cat’s life. Its nutritional purpose remains useful beside a complete diet: a full daily formula for the ordinary work of maintaining cells as a cat ages.

In a 30-cat study, a food blend containing blueberries and other antioxidant ingredients lowered blood markers of oxidative damage.

Silver tabby sitting beside a food bowl and a Hollywood Elixir box held in a person's hand

DVM Voice: Clinical Vignette of a Common Pattern in Senior Cat Aging

Case provided by JoAnna Pendergrass, DVM

Sasha, a 12-year-old cat, was brought in after her owner noticed increased thirst and urination, lethargy, vomiting, and a generally unkempt appearance. Examination showed weight loss, elevated blood pressure, and reduced vitality.

Diagnostic testing revealed elevated kidney markers, poorly concentrated urine, and protein loss in the urine — findings consistent with chronic kidney disease, one of the most common chronic conditions in senior cats.

Her care required a kidney-focused diet, blood pressure management, targeted supplementation, medication support, and regular monitoring — a necessary plan, but one started after clinical signs were already visible.

Clinical takeaway: Sasha’s case reflects why senior-cat wellness should begin before obvious decline. Earlier monitoring, body-condition tracking, hydration awareness, antioxidant support, and daily cellular resilience may help support quality of life as cats age.

Single-case vignette. Not generalizable. Veterinary diagnosis and monitoring are essential for increased thirst, urination, vomiting, lethargy, weight loss, or suspected kidney disease.

Explore Hollywood Elixir Research →
Woman holding a Hollywood Elixir box toward a brown cat perched on the back of a sofa

The full 17-active Hollywood Elixir declaration

The current panel lists the following amounts per full 2.5 g sachet. Forms and concentrations are part of the declaration. 10

  • Astaxanthin 2% (natural) — 2 mg
  • Vitamin E D-alpha Tocopheryl Acid Succinate 1210 — 15 IU
  • Beta Glucan (Beta-1,3/1,6-D-Glucan Powder) from Saccharomyces cerevisiae — 50 mg
  • Coenzyme Q10 98% (Ubidecarenone) — 40 mg
  • Vitamin B12 (as Methylcobalamin Trit 1% on DCP) — 0.25 mg
  • Nicotinamide Riboside Tartrate — 60 mg
  • L-Glutathione Reduced — 50 mg
  • Resveratrol Extract (Std. 98% from Polygonum Cuspidatum) — 15 mg
  • Quercetin Dihydrate 95% — 25 mg
  • Reishi Mushroom Powder P.E. (Std. 35% Polysaccharides) — 25 mg
  • Organic Spirulina Powder — 50 mg
  • Vitamin B3 (as Niacin) — 2 mg
  • Vitamin B6 (as Pyridoxal 5-Phosphate) — 1 mg
  • Vitamin B2 (as Riboflavin) USP — 0.5 mg
  • Blueberry Fruit Powder — 50 mg
  • Whey Protein Isolate 90% (WPI) — 250 mg
  • Vitamin C (as Ascorbic Acid) — 10 mg

Additional ingredients are Chicken Flavor, Chicken Liver Powder, Yeast Extract, Glycine and Hydroxypropyl Beta-Cyclodextrin. The B12 amount refers to the stated 1% trituration on DCP, not 0.25 mg of pure methylcobalamin. See the full Hollywood Elixir ingredient guide.

Woman leaning toward a fluffy orange cat beside a Hollywood Elixir box and green food bowl

How cellular energy and antioxidant nutrition connect

NAD+ helps cells turn nutrients from food into usable energy. Nicotinamide riboside, or NR, is one starting material cells can use to make NAD+. Normal mitochondrial energy transfer also involves CoQ, while riboflavin supplies the FMN and FAD cofactors used in energy reactions. 11 12 13

Antioxidant work has its own supporting chemistry. For example, the enzyme that recycles used glutathione draws on NADPH. These reactions explain why antioxidant ingredients can belong alongside energy-related nutrients in a wider formula. They do not establish that giving NR automatically raises a cat’s NADPH or glutathione. 14

Hollywood Elixir brings these related nutritional selections together with its food powders and extracts. The whole formula has a broader healthy-aging purpose than adding one plant compound to a meal. 10

See how cells make, use and recycle NAD+ in our NADome and NADomics guide.

Tabby cat licking its nose beside a food bowl and Hollywood Elixir box

Yeast, mushroom and protein complete a wider formula

Not every Hollywood Elixir ingredient is a plant antioxidant. The beta-glucan comes from Saccharomyces cerevisiae yeast; the reishi preparation is standardized to 35% polysaccharides. They are selected for the formula’s immune-support purpose, with their identities kept distinct from the polyphenol ingredients. 10

Whey protein isolate contributes amino acids within the formula. Its 250 mg declaration is a small ingredient amount, not a replacement for a cat’s dietary protein. The additional glycine has no separate amount declared.

This broader selection is part of the reason to choose the finished formula. It combines antioxidant ingredients with NAD+ precursor nutrition, cofactors and complementary selections for daily healthy aging, while the cat’s main food continues to supply complete nutrition.

Choosing a formula that fits the individual cat

The right addition fits the whole feeding and care plan. Before starting, have your veterinarian review the full label alongside any medicines and other supplements. This is especially useful when a cat has kidney disease, another medical condition or a history of reactions. 15

A food ingredient, concentrated extract and essential oil should not be treated as interchangeable simply because their plant names match. Use the actual cat-appropriate product and directions; do not recreate a research diet with household extracts.

Our cat vitamins and supplements guide and routine veterinary care guide can help place that choice alongside the rest of the cat’s care.

Making the prepared formula part of dinner

Current Hollywood Elixir adult directions are half a sachet below 7 lb, one sachet at 7–30 lb and two sachets above 30 lb daily, mixed with food. A full sachet is 2.5 g; its panel amounts are not the amounts in every weight-based portion. 10

Choose a familiar meal and notice whether the cat eats it. Acceptance is an individual response, even with a prepared powder. Keep fresh water available and pay attention to hydration. A supplement should fit the meal, not become a reason to miss it.

For an adult or senior cat, that is a practical benefit of the full formula: the related ingredients are already prepared together for a daily food routine.

Tabby cat sitting at a table with a food bowl and Hollywood Elixir box

Weight management needs complete nutrition, not an antioxidant patch

During a planned weight-loss program, the first job is a feeding plan that provides suitable nutrition at the chosen calorie intake. Have the veterinarian set the food and portions and review any additions. An antioxidant supplement does not make an unbalanced or insufficient meal complete. 3

Unplanned weight loss is a different situation. If your senior cat is losing weight or not eating, investigate the cause rather than using a supplement to compensate. Those observations do not identify an antioxidant deficiency.

Hollywood Elixir is an optional healthy-aging addition to suitable food, not a substitute for calories, a therapeutic diet or an assessment.

Woman cuddling a silver tabby and a cream-colored cat while holding a Hollywood Elixir box

What to watch—and why there is no universal results calendar

The feline studies measured specific laboratory outcomes over their own study periods. They do not provide a reliable countdown to a shinier coat, more energy or a longer life with Hollywood Elixir. A cat grooming less deserves attention in its own right, not an assumption about oxidative stress.

At home, note meal acceptance and any new digestive change. If a supplement causes upset, stop and contact the veterinarian; problems such as vomiting or diarrhea belong in a health assessment. Follow the manufacturer’s storage directions as well. 15

Food storage also matters: vitamins can lose activity and fats can become rancid with prolonged storage. That is different from saying a mineral such as selenium degrades like a vitamin. 3

A natural-source question can lead to a complete daily choice

Understanding natural sources gives you a clearer choice: adequate food first, followed by an addition with a purpose you can explain. You do not need to choose between dismissing every plant ingredient and treating every botanical as a remedy.

Hollywood Elixir brings its plant-derived selections into a full 17-active formula for cellular energy and antioxidant defense as cats age. The powders, extracts, vitamins and NAD+ precursor are prepared together, ready to join a familiar meal. 10

Explore Hollywood Elixir® for that daily healthy-aging role, or continue with our guides to supplements for older cats and anti-aging nutrition for cats.

Hollywood Elixir brings plant-derived ingredients into a full 17-active formula for cellular energy and antioxidant defense, prepared for a cat’s daily meal.

Educational content only. This material is not a substitute for veterinary advice. Always consult your veterinarian about your cat’s specific needs. These statements have not been evaluated by the Food and Drug Administration. Products mentioned are not intended to diagnose, treat, cure, or prevent any disease.

Glossary

Antioxidant: a substance involved in limiting damaging oxidation.

Glutathione: a molecule cells make from glutamate, cysteine and glycine and use in antioxidant reactions.

Polyphenols: a broad family of plant compounds, including compounds found in berries.

Carotenoid: a pigment family that includes astaxanthin and beta-carotene.

Extract: a preparation that selects or concentrates constituents from a source material.

Standardized preparation: an ingredient declared to contain a specified concentration of a constituent or group.

Biomarker: a measured biological indicator, such as a compound in blood; not automatically a clinical health outcome.

NAD+: a coenzyme cells use in nutrient metabolism and other cellular processes.

NR: nicotinamide riboside, a starting material for making NAD+.

Related Reading

Aging & Senior Cat Guidance
• Cat Age Calculator: Cat Years to Human Years
• Cat Lifespan by Breed
• Lethargy in Cats
• Senior Cat Not Eating
• Cat Drinking A Lot
• Why Is My Senior Cat Withdrawn?

Healthy Aging Support
• NAD+ for Cats
• NMN for Cats
• Vitamins For Older Cats
• Senior Cat Food
• Longevity Drugs for Cats

References

Numbered references identify the sources used for specific claims. Read the study design, species and evidence boundaries alongside each finding.

  1. Sanderson SL. Nutritional Requirements of Small Animals. 2024Evidence boundary: Veterinary nutrition guidance on feline vitamin A, vitamin E and vitamin C requirements and functions.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4
  2. Association of American Feed Control Officials. Natural. n.d.Evidence boundary: Official explanation of natural-source and processing terminology in pet-food labeling.↩ 1 · ↩ 2
  3. Cornell Feline Health Center. Feeding Your Cat. 2026Evidence boundary: Veterinary guidance on complete food, acceptance, storage and weight management.↩ 1 · ↩ 2 · ↩ 3
  4. Reactome. Glutathione synthesis and recycling. n.d.Evidence boundary: Curated normal glutathione synthesis and recycling, including the amino-acid building materials.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4
  5. National Center for Biotechnology Information. GPX1 glutathione peroxidase 1 [Homo sapiens (human)]. 2026Evidence boundary: Official GPX1 functional summary on glutathione-dependent peroxide reduction; human annotation.↩
  6. Panasevich M, Daristotle L, Lin CY, Frantz N. 126 Antioxidant-Containing Kibble Supplemented to Adult Cats Elicited Improvements in Antioxidant Outcomes and C-Reactive Protein. 2022· DOI 10.1093/jas/skac247.113Evidence boundary: Conference report of a 30-cat crossover food study, with measured blood outcomes and industry-affiliated authors.↩ 1 · ↩ 2
  7. Jewell DE, Panickar KS. Botanicals Reduce Circulating Concentrations of Cholesterol and Triglycerides and Work Synergistically With Arachidonic Acid to Reduce Inflammatory Cytokines in Cats. 2021· DOI 10.3389/fvets.2021.620447Evidence boundary: Study of four complete foods in 48 healthy cats, separating botanical and arachidonic-acid combinations; industry funding disclosed.↩
  8. Park JS, Mathison BD, Hayek MG, Massimino S, Reinhart GA, Chew BP. Astaxanthin stimulates cell-mediated and humoral immune responses in cats. 2011· DOI 10.1016/j.vetimm.2011.08.019Evidence boundary: Young-cat astaxanthin study measuring selected immune responses over 12 weeks.↩
  9. Kosmal PAL, Dilger RN, Bauer L, Saunders-Blades J, Shoveller AK. A berry small inclusion: 40 types of commercial dog and cat kibble with added blueberries provide low levels of quercetin, free phenolics, and alkali-labile phenolics. 2025· DOI 10.1093/jas/skaf258Evidence boundary: Chemical survey of 40 dog and cat foods listing blueberries; not an animal health trial.↩ 1 · ↩ 2
  10. La Petite Labs. Hollywood Elixir® ingredients and daily serving. 2026Evidence boundary: Manufacturer’s complete 17-active declaration, additional ingredients and adult portions.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4 · ↩ 5 · ↩ 6 · ↩ 7 · ↩ 8 · ↩ 9 · ↩ 10 · ↩ 11
  11. Fletcher RS et al. Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells. 2017· DOI 10.1016/j.molmet.2017.05.011Evidence boundary: Mouse and cell research on NR metabolism and NAD+ precursor pathways.↩
  12. Reactome. Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2. n.d.Evidence boundary: Curated mitochondrial electron-transfer reaction involving NADH and CoQ.↩
  13. Reactome. Vitamin B2 (riboflavin) metabolism. n.d.Evidence boundary: Curated riboflavin metabolism and its energy-related FMN/FAD cofactors.↩
  14. Reactome. glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+. n.d.Evidence boundary: Curated normal reaction in which NADPH supports glutathione recycling.↩
  15. Hyland K, Gollakner R. Antioxidants. 2025Evidence boundary: Veterinary overview of antioxidant products, individual precautions and possible adverse effects.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4

FAQ

What are natural antioxidants for cats in plain terms?

They include nutrients such as vitamin E, plant compounds and materials used by the body’s own antioxidant processes. Cats also make protective molecules such as glutathione. The source, preparation and amount matter: a whole fruit, fruit powder and concentrated extract do not supply identical quantities of their compounds. 1 4

Are natural antioxidants for cats safe for daily use?

Safety depends on the ingredient, portion and cat. Natural origin does not guarantee safety. Review a new product with your veterinarian and follow its cat-specific directions. 2 15

Which cats should avoid antioxidant supplements without vet approval?

Seek review for cats with chronic disease, prior reactions or prescribed medicines, and before giving an adult formula to a kitten or pregnant cat. Bring the full label.

How much antioxidant supplement should I give my cat?

Use the directions for the specific product. Current adult Hollywood Elixir portions are half a sachet below 7 lb, one at 7–30 lb and two above 30 lb daily, mixed with food. A full sachet is 2.5 g. Research doses for individual compounds are not substitute serving directions. 10

What side effects can antioxidants cause in some cats?

Digestive upset and allergic reactions are possible. Stop a product causing a reaction and contact your veterinarian. Breathing difficulty or facial swelling needs immediate veterinary attention. 15

How long until I notice results from antioxidant support?

There is no established visible-results timetable for Hollywood Elixir from the studies described here. Those trials measured particular outcomes with their own foods or ingredients. Track acceptance and tolerance, and have changes in appetite, weight or usual behavior assessed instead of treating them as an antioxidant test.

Do antioxidants help cats during weight loss programs?

A weight-loss plan should preserve complete nutrition at an appropriate calorie intake. Supplements do not correct an inadequately balanced meal. Ask the veterinarian to review the diet and additions together; the studies discussed here do not establish that Hollywood Elixir improves feline weight-loss outcomes.

How do I choose among the best natural antioxidants for cats?

Match the purpose to the cat, then consider the full formula and actual ingredient forms. Hollywood Elixir’s 17-active NAD+ system brings plant-derived selections, vitamins, glutathione and cellular energy nutrition together for daily healthy aging. It offers a prepared whole-formula choice alongside complete food. 10

Orange-and-white cat beside a Hollywood Elixir box held in a person's hand

Discover LPL-01: How This Fits Into a Larger Feline Longevity System

Aging in cats unfolds quietly. It’s not driven by a single failure, but by gradual shifts across interconnected systems — cellular energy, oxidative balance, immune tone, and tissue integrity — each influencing the others over time.

This article explores one layer of that system. To understand what actually shapes long-term health, you need to step back and look at how these layers interact.

Start with the underlying science:

Keep exploring

What would you like to understand next?

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