PetDomain, formerly ThorneVet, vs Hollywood Elixir® for Dogs

Compare the complete formulas, current labels and daily cost for your dog

By La Petite Labs Editorial 22 min read

As Seen On

Woman hugging a golden retriever while holding a Hollywood Elixir box
Contents

PetDomain Longevity Complex is the current product line formerly sold as ThorneVet. Its appeal is a defined combination of taurine, nicotinamide riboside and plant compounds, available as a soft chew or powder. Hollywood Elixir® takes a broader approach: 17 actives that bring NAD+ precursor support together with mitochondrial cofactors, antioxidant nutrients and ingredients selected to support immune health. 1 2 3 6

The choice starts with that nutritional purpose. A chew may suit a dog who takes treats readily; a prepared sachet may suit an owner who wants Hollywood Elixir’s connected formula with a meal. Both brands disclose active amounts, and both offer a powder format. Their serving directions—and the cost for a particular dog—differ.

This comparison is published by La Petite Labs, the maker of Hollywood Elixir. It uses the current PetDomain panels and La Petite Labs product information.

ThorneVet is now PetDomain: use the current label

PetDomain’s name-change information identifies it as the former ThorneVet business and says the familiar team and products continue. Its current Longevity Complex listings use PD985-SC for soft chews and PD985-P for powder. Those current listings are the basis of this comparison. 1 2 3

One label detail deserves attention if you have older packaging. The current panel names nicotinamide riboside tartrate; a 2024 ThorneVet PDF names nicotinamide riboside hydrogen malate. Both print 100 mg per chew. That public wording difference does not establish whether there was a formulation change, a supplier change or a labeling correction. Use the package you are buying and ask PetDomain to clarify an apparent mismatch. 4 5

“Formerly ThorneVet” helps connect an old recommendation to the current brand. It should not turn historical specifications into current facts.

At a Glance

What is PetDomain Longevity Complex, formerly ThorneVet?

A seven-active supplement offered as a 90-chew jar or a 90-scoop powder. Its current formula includes taurine, NR tartrate, three phytosome preparations, trans-resveratrol and astaxanthin. 1 3 4

Product
PetDomain Longevity Complex, formerly ThorneVet
Category
Daily healthy-aging supplement for dogs and cats; this comparison uses dog directions.
Format
90 soft chews or 90 powder scoops; dogs: one chew or scoop per 25 lb, one to two times daily.
Why owners notice it
Seven declared actives, including taurine, NR tartrate and three branded phytosome preparations; a choice of chew or powder.
What to check
Current PD985-SC or PD985-P package, active and non-active ingredients, serving frequency and full caution panel. Current NR tartrate wording differs from the legacy hydrogen-malate PDF.
Common shopping questions

Is PetDomain Longevity Complex a useful option for dogs?

It offers clear ingredient amounts and two formats. It is a useful option when its taurine and phytosome composition fits the intended nutritional purpose and the dog’s feeding plan. The label alone does not establish a lifespan benefit.

How does Hollywood Elixir differ?

Hollywood Elixir combines 17 actives, including NR, CoQ10, reduced glutathione, B vitamins, yeast beta-glucans, reishi and food-based ingredients. Its design connects NAD+ precursor support with mitochondrial cofactors and antioxidant and immune nutrition. 6

Does PetDomain disclose its active amounts?

Yes. The current panels show each of seven active amounts per 3 g chew or 2.0 cc/1.25 g scoop. Hollywood Elixir also declares its 17 ingredient amounts per full 2.5 g sachet. 3 4 6

What should I check before buying?

Match the current product, format, ingredient and caution panels to the package being sold. Use the dog’s weight and agreed frequency to calculate daily quantity and cost. Current PetDomain NR wording differs from an older ThorneVet PDF. 4 5

Can either formula replace veterinary care or a prescribed diet?

No. These formulas have supplemental nutritional purposes. New symptoms, ongoing treatment and a prescribed diet need their own care plan; the supplement should be reviewed within it.

Which is easier to serve to a large dog?

That depends on acceptance and format. PetDomain offers chews or loose powder; Hollywood Elixir offers prepared sachets. At 75 lb, PetDomain’s directions give three units once or twice daily; Hollywood Elixir’s table gives two sachets daily. 3 4 7

Does PetDomain have a public lot-level COA lookup?

A public lookup was not established in the current PetDomain pages reviewed here. This does not establish an absence of testing; request the relevant lot documents. La Petite Labs provides a public COA Lookup route for Hollywood Elixir. 15 16

What could make PetDomain less suitable for my dog?

Its seven-active composition may not match an owner seeking the CoQ10, glutathione and broader cofactor combination in Hollywood Elixir. Cost also rises with weight and frequency. Conversely, its chew option and lower-cost examples may make it the better fit.

Why choose Hollywood Elixir for a senior dog?

Choose it for the full 17-active cellular nutrition design: NAD+ precursor support alongside mitochondrial cofactors, antioxidants and ingredients selected to support immune health. Its role is daily nutrition alongside the dog’s food and care, not a treatment for a new age-related symptom. 6

Which product has better ingredient disclosure?

Both show active amounts. Hollywood Elixir has more declared active rows, while PetDomain specifies branded preparations for several ingredients. Read the exact forms and serving basis; a higher count or printed amount does not establish clinical superiority. 4 6

Which product should I choose?

Choose Hollywood Elixir for its broader connected cellular nutrition system. Choose PetDomain when its taurine/phytosome composition, chew option or the relevant lower-cost example is the closer fit. Use the complete current label and your dog’s daily serving to make the final choice.

Side by Side

The Plain Comparison

PetDomain and Hollywood Elixir offer different complete formulas. Compare their current composition, formats, daily amounts and matched costs before choosing for your dog.

questioncompetitorhollywoodwinner
Main appealTaurine, NR tartrate and phytosome-focused seven-active formula.17-active cellular nutrition with NAD+ precursor support, CoQ10, glutathione, vitamins and ingredients selected to support immune health.Hollywood Elixir for the broader connected design; PetDomain for its specific taurine/phytosome composition.
Daily servingOne chew or scoop per 25 lb, once or twice daily; 75 lb means three or six units daily.Half a sachet under 7 lb; one at 7–30 lb; two over 30 lb daily.Choose the appropriate formula and follow its current serving; frequency affects cost.
Active disclosureSeven ingredient amounts per 3 g chew or 2.0 cc/1.25 g scoop.17 ingredient amounts per full 2.5 g sachet, with current forms specified.Both provide quantities; compare forms and daily amounts, not ingredient count alone.
Quality accessManufacturer describes NASC participation and testing; no public lot lookup established in reviewed pages.Public COA Lookup route and manufacturer quality information.Hollywood Elixir for public lookup access; inspect the actual matching report and its tests.
FormatSoft chew or loose powder with different non-active ingredients.Prepared powder sachets for mixing into food.PetDomain for format choice; Hollywood Elixir for its formula in prepared sachets.
90-day one-time cost25 lb: chews $77/$154 or powder $74/$148; 75 lb: chews $231/$462 or powder $222/$444, once/twice daily.25-lb Standard: $199; 75-lb Double: $379. USD, October 3, 2026, before tax/shipping.PetDomain in both 25-lb examples and once daily at 75 lb; Hollywood Elixir versus twice-daily PetDomain at 75 lb.

Competitor label and pricing facts checked 2026-10-03. Sources are listed in the References section below.

Woman holding a Hollywood Elixir box beside a pug, a terrier and a food bowl

The practical choice between the two formulas

Choose PetDomain when its taurine and phytosome ingredients match the nutritional purpose you and your veterinarian have in mind, or when a chew is the easiest accepted format. Its seven active lines give you clear quantities, and the separate powder provides another way to serve them. 3 4

Choose Hollywood Elixir when you want broader daily cellular nutrition in one formula: NR alongside CoQ10, reduced glutathione, B vitamins, other antioxidants and ingredients selected for immune support. It brings different nutritional roles into a prepared powder instead of asking you to assemble that particular combination yourself. 6

Price can settle a close choice, but it needs the dog’s weight and the intended frequency. The 90-day examples below show where PetDomain costs less and where Hollywood Elixir does. The wider dog longevity supplement guide provides context if your shortlist extends beyond these two.

Woman in sportswear holding a Hollywood Elixir box beside a black-and-tan dog outdoors

What the current PetDomain formula contains

The current soft-chew panel declares the following amounts per 3 g chew. The powder declares the same active amounts per 2.0 cc scoop, weighing 1.25 g. 3 4

  • Taurine: 500 mg.
  • Nicotinamide riboside tartrate: 100 mg.
  • Quercetin phytosome, QuerceFit®: 75 mg.
  • Curcumin phytosome, CurcuVET®: 50 mg.
  • Decaffeinated green tea phytosome, GreenSelect®: 50 mg.
  • Trans-resveratrol, Veri-te™: 40 mg.
  • Astaxanthin from AstaReal® biomass: 3 mg.

The three phytosome lines combine their plant extracts with a sunflower phospholipid complex. They are particular ingredient preparations, not simply the same milligrams of a pure plant compound. The formula also has different non-active ingredients in its chew and powder versions, discussed below.

These are useful details for a purchasing decision: you can identify the preparation, the amount and the quantity of product that supplies it.

Woman holding a Hollywood Elixir box above her forehead beside a Bernese mountain dog outdoors

From food energy to cellular energy: why the formula matters

Food supplies the fuel for movement and daily body maintenance. Within cells, chemical reactions turn that fuel into usable energy. NAD+ and its reduced partner, NADH, help carry electrons through those reactions. NR is one of the precursors cells can use to make NAD+. 8 12

CoQ10 has a different job. It carries electrons within the mitochondrial energy machinery. NADH passes electrons into that machinery, and CoQ helps move them onward. A precursor for making NAD and an electron carrier therefore address different parts of normal energy metabolism. 9

That relationship explains a central Hollywood Elixir design choice: its NR sits alongside CoQ10 and B-vitamin cofactors. PetDomain includes NR, but its other six active lines follow a different design. This is a reason to compare the complete formula, beyond the largest NR number. 4 6

Our NAD+ for dogs guide explains the cofactor, while the NR guide looks more closely at the precursor.

See how cells make, use and recycle NAD+ in our NADome and NADomics guide.

Golden retriever nuzzling a woman holding a Hollywood Elixir box on the grass beside a food bowl

Antioxidant nutrition belongs beside energy metabolism

Cells also maintain systems that manage oxidation. Glutathione is part of that network. After becoming oxidized, it can be returned to its reduced form by an enzyme that uses NADPH, a related cofactor, and FAD, which comes from riboflavin. This is a recycling process within normal cell biology. 10 11

Hollywood Elixir includes reduced glutathione, riboflavin, vitamin C and vitamin E within its wider antioxidant design. Vitamins C and E have antioxidant roles; B vitamins contribute to enzyme systems. Dogs already make vitamin C, so including it does not mean every older dog is deficient. 6 12

Hollywood Elixir brings precursor, cofactor and antioxidant nutrition together. The molecular relationships explain its design; they do not establish that the finished blend has improved those processes in a clinical trial. For the wider subject, see antioxidant nutrition for dogs.

NR is a precursor used to make NAD, while CoQ10 carries electrons within mitochondria. Their different jobs explain why both belong in Hollywood Elixir’s cellular nutrition design.

Hollywood Elixir’s full 17-active declaration

Hollywood Elixir declares these ingredient forms and amounts per full 2.5 g sachet. The quantities below retain the current ingredient preparations as stated, including standardized powders and diluted preparations. 6

  • Nicotinamide riboside tartrate: 60 mg.
  • Coenzyme Q10 98% (ubidecarenone): 40 mg.
  • L-glutathione reduced: 50 mg.
  • Vitamin B3, as niacin: 2 mg.
  • Vitamin B2, as riboflavin: 0.5 mg.
  • Vitamin B6, as pyridoxal 5-phosphate: 1 mg.
  • Vitamin B12, as methylcobalamin trituration 1% on DCP: 0.25 mg.
  • Vitamin C, as ascorbic acid: 10 mg.
  • Vitamin E, D-alpha tocopheryl acid succinate 1210: 15 IU.
  • Astaxanthin 2% (natural): 2 mg.
  • Resveratrol extract, standardized to 98%, from Polygonum cuspidatum: 15 mg.
  • Quercetin dihydrate 95%: 25 mg.
  • Yeast beta-1,3/1,6-D-glucan powder: 50 mg.
  • Reishi mushroom extract, standardized to 35% polysaccharides: 25 mg.
  • Organic spirulina powder: 50 mg.
  • Blueberry fruit powder: 50 mg.
  • Whey protein isolate 90%: 250 mg.

The additional ingredients listed are chicken flavor, chicken liver powder, yeast extract, glycine and hydroxypropyl beta-cyclodextrin. The complete ingredient guide provides the current declaration.

The formula combines ingredients selected for cellular energy, antioxidant defense and immune support. Whey contributes a small protein component; the sachet is an addition to the dog’s diet, not its main protein source.

Overhead view of a black-and-white dog beside a food bowl and Hollywood Elixir box

The yeast, mushroom and food-based side of the formula

Hollywood Elixir’s design also includes yeast beta-glucans, reishi, spirulina and blueberry. These extend the formula beyond NAD-related ingredients into polysaccharide and food-based components selected for its immune and phytonutrient purpose. 6

There is actual canine feeding research behind interest in some of these ingredients. In a 42-week study, 30 adult Husky crosses received complete food with or without 0.2% dried spirulina. The spirulina group had higher fecal IgA and higher antibody responses to a rabies vaccine at specified assessment times. IgA is an antibody involved in mucosal defense. 13

That study examined immune markers in adult dogs, not longer life or Hollywood Elixir. Its food concentration cannot be equated with the sachet’s 50 mg declaration. Within Hollywood Elixir, spirulina joins yeast, mushroom and other food-based ingredients in the broader daily formula.

Woman smiling beside a golden retriever, a green food bowl and a Hollywood Elixir box

Compare ingredient forms as well as milligrams

PetDomain prints 100 mg of NR tartrate per chew or scoop; Hollywood Elixir prints 60 mg per sachet. Your dog’s daily totals then depend on each product’s directions. These are declared ingredient quantities, not a measurement of how much NAD+ the dog will make or a ranking of clinical benefit. 3 4 6

The surrounding forms differ too. PetDomain’s quercetin line is a phytosome complex; Hollywood Elixir declares quercetin dihydrate 95%. Its astaxanthin line specifies a 2% preparation, while PetDomain names an AstaReal biomass source. Treat those descriptions as part of the amount, rather than comparing the printed milligrams as if every line were a pure, identical substance.

For the purchase decision, ask what the whole daily formula contributes. Hollywood Elixir includes CoQ10 and reduced glutathione; PetDomain includes taurine and curcumin and green tea phytosomes. Those are substantive composition differences.

Man holding a Hollywood Elixir box while sitting on an outdoor sofa with a golden retriever

Chew, loose powder or prepared sachet

PetDomain gives you a chew and a loose-powder choice. The chew includes ingredients that make the texture and flavor, including chickpea flour, tapioca starch, oils, gums and a vegan bacon flavor. The current powder lists flaxseed and silicon dioxide as inactive ingredients. A dog with a restricted diet needs the complete list for the selected format. 3 4

Hollywood Elixir comes in prepared sachets for mixing with food. That packaging portions the formula; the dog’s weight determines whether the daily serving is half, one or two sachets. Its whey and chicken ingredients also matter to a restricted feeding plan. 6 7

Both powders can accompany a meal. A soft chew offers a different experience for a dog who readily accepts it. Choose a format your dog accepts and you can use consistently, with a portion that is easy to measure.

Hollywood Elixir’s declared protein ingredient is whey isolate. If you are also comparing hydrolyzed proteins, our hydrolyzed whey guide explains that separate ingredient category; the terms should not be silently exchanged.

The current daily directions, by dog weight

PetDomain’s directions specify one chew or one scoop per 25 lb, one to two times daily. For a 25-lb dog that means one or two units daily. For a 75-lb dog it means three or six. A 90-unit container therefore lasts 90 or 45 days in the first example, and 30 or 15 days in the second. 3 4

Hollywood Elixir’s current daily table states:

  • Under 7 lb: half a sachet.
  • 7–30 lb: one sachet.
  • Over 30 lb: two sachets.

A 25-lb dog uses the Standard serving; a 75-lb dog uses Double. Ninety days requires 90 or 180 sachets respectively. 7

These are the manufacturers’ directions used for the examples. Agree on the appropriate product and frequency for a dog receiving treatment before calculating the order. Choosing a frequency solely to obtain the cheaper price would skip the purpose of the supplement.

In a 30-dog feeding study, a diet containing 0.2% spirulina produced higher antibody responses to a rabies vaccine at several measured time points.

Spotted gray dog beside a Hollywood Elixir box held in a person's hand

What research can—and cannot—decide here

Normal biology explains why NR, CoQ10, glutathione and related nutrients interest researchers. Ingredient studies can then ask more specific questions about a particular preparation, amount and population. The canine spirulina study is one example of that second step. 8 9 13

A finished-formula comparison would be a different test. The evidence reviewed for this article did not establish a clinical head-to-head trial of current PetDomain Longevity Complex and Hollywood Elixir, or a lifespan benefit for either finished blend.

You can still make a meaningful choice. The verified differences are what each formula contains, its intended nutritional design, its format, the dog’s daily amount, cost and accessible quality information. Those are the reasons developed here. Customer stories and a favorable change after starting a supplement cannot isolate its effect from food, treatment, activity or other changes.

Golden retriever nuzzling a man holding a Hollywood Elixir box beside a food bowl

A fair 90-day cost comparison

These USD one-time purchase examples, checked October 3, 2026, exclude tax and shipping. PetDomain sells 90 chews for $77 or 90 powder scoops for $74. Hollywood Elixir’s Standard 90-sachet pack is $199; Double 180 is $379. 2 3 7

For a 25-lb dog, 90 days costs:

  • PetDomain chews: $77 once daily or $154 twice daily.
  • PetDomain powder: $74 once daily or $148 twice daily.
  • Hollywood Elixir Standard: $199 at one sachet daily.

For a 75-lb dog, 90 days costs:

  • PetDomain chews: $231 once daily or $462 twice daily.
  • PetDomain powder: $222 once daily or $444 twice daily.
  • Hollywood Elixir Double: $379 at two sachets daily.

PetDomain costs less in the 25-lb example at either frequency. At 75 lb, it costs less once daily; Hollywood Elixir costs less than either twice-daily PetDomain format. The result depends on the serving plan, not just the container price.

Subscriptions are separate offers. The displayed PetDomain discount is 10%, making a jar $69.30 for chews or $66.60 for powder; select a delivery cadence that matches use. Hollywood Elixir Standard starts from $50/month: $149 for the first 90 days with the welcome offer, then $169 every 90 days. Double is $269 for the first 90 days with the welcome offer, then $319 every 90 days, rather than that amount each month. Check current checkout terms before ordering. 2 3 7

Golden spaniel eating from a green bowl beside a Hollywood Elixir box

Quality information you can inspect

PetDomain states that it manufactures in the United States and describes ingredient sourcing and testing. Its About page reports NASC membership since 2002, on-site audits every two years and the NASC Quality Seal on qualifying products. The current Longevity Complex panels display that seal. 4 14 15

La Petite Labs states that Hollywood Elixir is made in a cGMP-compliant, NASC Preferred Supplier facility and provides a public COA Lookup for batch testing information. A supplier-facility description and a product’s NASC seal are different claims; neither is proof of a longevity benefit. 16

The practical distinction is access to a public lookup route. A comparable PetDomain public lot lookup was not established in the pages reviewed here. That does not mean PetDomain performs no testing or cannot provide documents on request.

For either brand, match a report to the product and lot, then read which substances or contaminants were actually measured. A contamination result is not automatically a potency test for every active. The supplement quality guide explains that distinction.

When PetDomain is the better fit

PetDomain is a clear option when you specifically want its taurine-containing combination or its three phytosome preparations. Hollywood Elixir does not reproduce those seven active lines. A dog who accepts a soft chew readily may also make that format the practical choice. 4 6

Cost is another real reason. The matched 25-lb example favors PetDomain at either labeled frequency, and the 75-lb example favors it at once-daily use. The loose powder is slightly less expensive per 90-unit container than the chews. 2 3

If that composition already fits a veterinarian’s plan and the dog accepts it, the label and format provide a straightforward reason to stay with it. A broader ingredient list elsewhere does not erase a well-matched purpose.

Why choose Hollywood Elixir’s broader system

Choose Hollywood Elixir when you want connected cellular nutrition in one daily formula. Its NR and niacin contribute to its NAD+ support design; CoQ10 and B-vitamin cofactors bring the energy-metabolism side; reduced glutathione and other antioxidant nutrients address the accompanying defense system. Yeast beta-glucans, reishi, spirulina, blueberry and the protein component complete its broader formulation. 6

That is more than a senior multivitamin. The appeal is a purposeful combination of precursor support, mitochondrial cofactors, antioxidants and ingredients selected to support immune health. You can inspect all 17 actives and their amounts. It suits an owner who wants that integrated design without choosing separate products to reproduce it.

Prepared sachets make the chosen formula part of a meal, and the public quality route gives you somewhere to inspect batch information. Explore what Hollywood Elixir is to see the complete system and current options. 7 16

Woman holding a Hollywood Elixir box beside a dapple dachshund and green food bowl on a sofa

Keep the supplement within the dog’s wider care

A senior dog still needs food that meets its nutritional needs, suitable calories, activity it can manage and attention to body and muscle condition. Those priorities can change with health and age. The AAHA senior-care guidance places nutritional assessment within that broader picture. 17

A supplement can have a defined place alongside it. Hollywood Elixir’s purpose is cellular healthy-aging nutrition; a prescribed diet, pain plan or treatment for a new symptom has its own job. The senior supplement guide helps separate those goals, and routine senior-dog veterinary care gives the clinical context.

Keep observations useful and ordinary: meal acceptance, stools, usual activity and any new difficulty. The senior-pet baseline tracker can organize those notes. They help a conversation about the dog; they are not a home test proving a supplement has slowed aging.

Woman cuddling a brown-and-white spaniel while holding a Hollywood Elixir box

Before starting, switching or combining

Bring the current full labels and the intended daily amounts to the clinician who knows your dog, particularly when there are medications, a restricted diet or an ongoing condition. Compare overlapping ingredients across products before adding another formula.

The current PetDomain web gallery inspected for this article supplied ingredient and direction panels, but not a complete current caution panel. Read the physical package or request the full current instructions. Older ThorneVet warnings should not be presented as an exhaustive substitute for today’s label. 4 5

Hollywood Elixir is positioned for adult and senior pets; use for puppies or pregnant or nursing pets requires veterinary direction. Its whey and chicken ingredients belong in any food-reaction review. If a new product coincides with vomiting, diarrhea or reduced appetite, pause it and seek advice rather than assuming an adjustment period is required. 6 7

Bring the full cellular nutrition system to their bowl

Hollywood Elixir earns its place through the way its ingredients are combined: NAD+ precursor support, mitochondrial cofactors, antioxidant nutrients and ingredients selected to support immune health in one 17-active formula. Choose Hollywood Elixir for that broader daily system, then select the current serving and purchase plan for your dog. 6 7

PetDomain remains a useful choice for its taurine and phytosome composition, format options and the lower-cost examples identified above. The decision is clearest when the formula’s purpose fits the dog and the daily amount fits the household.

Explore Hollywood Elixir’s current purchase options, with the complete ingredient declaration and serving guidance in view.

Choose Hollywood Elixir for broader daily cellular nutrition, with ingredients selected for energy metabolism, antioxidant defense and immune support in one prepared formula.

Educational content only. This material is not a substitute for veterinary advice. Always consult your veterinarian about your dog’s specific needs. These statements have not been evaluated by the Food and Drug Administration. Products mentioned are not intended to diagnose, treat, cure, or prevent any disease.

Glossary

  • Nicotinamide riboside (NR): A precursor cells can use to make NAD+.
  • NR tartrate: The NR ingredient form named on both current product declarations.
  • NAD+/NADH: Related forms of a cofactor pair involved in cellular energy reactions.
  • CoQ10: An electron carrier within mitochondrial energy machinery.
  • Glutathione: A molecule involved in cellular antioxidant systems.
  • Phytosome: A plant-extract and phospholipid preparation; the complex’s mass is not automatically pure extract mass.
  • Taurine: An amino acid included in PetDomain’s current formula.
  • COA: Certificate of Analysis, identifying the tests and results reported for a sample or batch.
  • Serving basis: The quantity of product represented by the listed ingredient amounts.
  • One-time versus subscription: A single purchase versus recurring orders under the chosen billing and delivery terms.

Related Reading

Aging & Senior Dog Guidance
• Dog Age Calculator
• Dog Lifespan by Breed
• Dog Dementia
• Lethargy in Dogs
• My Dog Won't Eat
• Dog Pacing At Night
• Dog Licking Paws
• Can Dogs Dehydrate

Healthy Aging Support
• NAD+ for Dogs
• NMN for Dogs
• Antioxidants Supplements for Dogs
• Best Senior Dog Supplements & Vitamins
• Rapamycin for Dogs

References

Product facts, public claims, ingredient details, and quality-language checks were checked against the references below.

  1. Brand sourceNew Name, Same Trusted FormulasOfficial name-change information connects the former ThorneVet business with PetDomain.
  2. Brand sourceLongevity ComplexCurrent manufacturer chew listing, package count, SKU and displayed prices; checked October 3, 2026.
  3. Brand sourceLongevity Complex PowderCurrent powder listing and official panels establish scoop size, ingredients, directions and prices.
  4. Brand sourceCurrent PetDomain Longevity Complex soft-chew ingredient and direction panelsOfficial current chew panel gives seven declared ingredient amounts and form descriptions.
  5. Brand sourceLegacy ThorneVet Longevity Complex soft-chew product sheetHistorical ThorneVet document shows the older NR hydrogen-malate wording; it is not the current label.
  6. Brand sourceHollywood Elixir®: current ingredient declarationCurrent manufacturer ingredient declaration, with amounts per full 2.5 g sachet; composition is distinct from a clinical outcome.
  7. Brand sourceHollywood Elixir® Longevity System: serving and purchase optionsCurrent manufacturer serving table and purchase options support the weight and price examples.
  8. Research sourceNicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cellsPrimary mouse-cell research explains NR metabolism; used here for pathway biology, not a dog outcome.
  9. Institutional sourceComplex I oxidises NADH to NAD+, reduces CoQ to CoQH2Curated molecular pathway identifies the distinct electron-transfer roles of NADH and CoQ.
  10. Institutional sourceglutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+Curated reaction explains glutathione recycling with NADPH; it does not test a supplement blend.
  11. Institutional sourceRiboflavin: Fact Sheet for Health ProfessionalsNormal cofactor biology only; human intake and treatment recommendations are not applied to dogs.
  12. Institutional sourceNutritional Requirements of Small AnimalsVeterinary nutrition guidance explains food energy, vitamin roles and the foundation of a balanced diet.
  13. Research sourceSupplementation of Diets With Spirulina Influences Immune and Gut Function in DogsA controlled 30-dog feeding study at 0.2% spirulina measured immune responses; neither comparison product was tested.
  14. Brand sourceAbout UsManufacturer account of NASC membership, audits and product-seal eligibility.
  15. Brand sourceIngredientsManufacturer ingredient, sourcing and US-manufacturing information; not an independently audited lot report.
  16. Brand sourcePublicly verified lab results and COA LookupPublic manufacturer quality-information route; the tests in an individual report define what it establishes.
  17. Institutional sourceNutrition — 2023 AAHA Senior Care Guidelines for Dogs and CatsOfficial senior-care nutrition guidance places supplements within food, body-condition and clinical care.

FAQ

Dalmatian looking toward a Hollywood Elixir box held in a person's hand

Discover LPL-01: How This Fits Into a Larger Canine Longevity System

Aging in dogs is not driven by a single pathway. It’s the result of interacting biological systems—energy metabolism, oxidative stress, immune signaling, and structural integrity—changing over time.

This article explores one piece of that puzzle. If you want to understand how these pieces connect—and what actually moves the needle—you need to zoom out.

Start with the underlying science: