The 12 Hallmarks of Aging in Dogs, Explained
Read full insightNiacin for Cats
By La Petite Labs Editorial 17 min read
References
Numbered references identify the sources used for specific claims. Read the study design, species and evidence boundaries alongside each finding.
-
NIH Office of Dietary Supplements. Niacin — Health Professional Fact Sheet. Evidence boundary: NIH explains niacin names, food sources and the roles of NAD and NADP in energy, synthesis and antioxidant chemistry. This is human nutrition guidance; its human intake recommendations and toxicity thresholds are not used as cat doses.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4 · ↩ 5 · ↩ 6 · ↩ 7 · ↩ 8 · ↩ 9 · ↩ 10
-
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP). Assessment of a feed additive consisting of niacinamide for all animal species for the renewal of its authorisation. Evidence boundary: EFSA assessed a specified niacinamide feed additive and concluded that it remained safe under its authorized conditions of use. This supports nutritional use in animal feed, rather than the safety of arbitrary amounts or cosmetic mixtures.↩ 1 · ↩ 2 · ↩ 3
-
Laura Stern. Toxicoses in Animals From Human Multivitamins and Supplements. Evidence boundary: Veterinary toxicology guidance covers the importance of the whole supplement, gastrointestinal effects of B vitamins, and flushing or itching associated with niacin in pets. It does not give a feline niacinamide threshold or a cosmetic drying-time rule.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4 · ↩ 5 · ↩ 6 · ↩ 7 · ↩ 8
-
Rachel S Fletcher et al. Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells. Evidence boundary: Mouse muscle and cell experiments examine NAD precursor pathways and NR-kinase activity. The pathway explanation distinguishes nicotinic acid, nicotinamide and NR; the experiments are not oral supplement trials in cats.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4 · ↩ 5 · ↩ 6
-
Masayuki Ikeda et al. Studies on the Biosynthesis of Nicotinamide Adenine Dinucleotide. II. A Role of Picolinic Carboxylase in the Biosynthesis of NAD from Tryptophan in Mammals. Evidence boundary: Cat and rat liver-enzyme experiments show how a competing breakdown route can limit niacin production from tryptophan. This was biochemical research, not a feline supplement-dose trial.↩ 1 · ↩ 2
-
FEDIAF. Nutritional Guidelines for Complete and Complementary Pet Food for Cats and Dogs. Evidence boundary: The feline tables give minimum recommended nutrient concentrations for complete food on specified energy-intake bases. They support the worked food-niacin calculation, not an additional supplement dose or a safe upper limit.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4 · ↩ 5 · ↩ 6
-
Amanda N. Dainton et al. Effects of container type and size on thermal processing characteristics and B-vitamin retention of canned cat food. Evidence boundary: This food-processing experiment measured B vitamins before and after retorting. Niacin did not change significantly under the tested conditions. The study used an enriched experimental premix to aid measurement and did not feed the food to cats.↩ 1 · ↩ 2
-
Sherry Lynn Sanderson. Nutritional Requirements of Small Animals. Evidence boundary: Merck’s veterinary nutrition review describes the cat’s dietary niacin dependence, the uncommon occurrence of deficiency with adequate food, and poor growth, diarrhea and weight loss reported in niacin-depleted kittens.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4 · ↩ 5
-
Aarti Kathrani et al. The effects of a hydrolyzed protein diet on the plasma, fecal and urine metabolome in cats with chronic enteropathy. Evidence boundary: Cats with intestinal disease ate a complete hydrolysed-soya diet for six weeks. Urinary N-methylnicotinamide increased in both centre cohorts, with dietary supply and absorption among the proposed explanations. Sample availability varied by centre and visit. The whole-food intervention did not isolate a niacin treatment. Funding included the American Academy of Veterinary Nutrition and Waltham.↩ 1 · ↩ 2 · ↩ 3
-
Kayla Hyland, Rania Gollakner. Niacinamide. Evidence boundary: This veterinary handout describes niacinamide use with other medicines for inflammatory skin disease in dogs, possible adverse effects and prompt contact after suspected overdose. It does not establish a feline coat benefit or a general cat supplement dose.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4 · ↩ 5
-
Reactome. Glutathione reduction using NADPH. Evidence boundary: A curated human reaction record describes glutathione reductase using NADPH to restore reduced glutathione. It supplies normal biochemical background, rather than evidence of a finished supplement’s effect in cats.↩ 1 · ↩ 2 · ↩ 3
-
Jessica Quimby, Sheri Ross. Diets for Cats with Chronic Kidney Disease (CKD). Evidence boundary: IRIS explains renal-diet composition, phosphorus control, individualized use of phosphate binders and adequate calorie intake. Its guidance concerns the whole clinical feeding plan, not an oral niacinamide replacement regimen.↩ 1 · ↩ 2
-
La Petite Labs. Hollywood Elixir: Supplement Facts and Cat Directions. Evidence boundary: The full 2.5 g sachet lists 2 mg niacin and 60 mg NR. Lite is half a sachet daily for under 7 lb or sensitive pets; Standard is one sachet for 7–30 lb. The powder is mixed into usual food and served immediately; the product also gives life-stage and consultation guidance.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4 · ↩ 5 · ↩ 6 · ↩ 7 · ↩ 8 · ↩ 9 · ↩ 10
-
La Petite Labs. Hollywood Elixir Ingredients. Evidence boundary: The active ingredient guide identifies NR tartrate, reduced L-glutathione and CoQ10. The B3 entry is simply “Vitamin B3 (as Niacin),” without specifying nicotinic acid or nicotinamide.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4
-
Reactome. Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2. Evidence boundary: This curated human reaction record follows electrons from NADH through Complex I to coenzyme Q. It explains an energy-transfer relationship, not the clinical performance of a feline combination supplement.↩
Keep exploring
What would you like to understand next?
Search practical guides about healthy aging, cellular energy, ingredients, and daily support for cats.

