The 12 Hallmarks of Aging in Dogs, Explained
Read full insightVitamin B for Cats
By La Petite Labs Editorial 21 min read
References
Numbered references identify the sources used for specific claims. Read the study design, species and evidence boundaries alongside each finding.
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Reactome. Metabolism of water-soluble vitamins and cofactors. Species/context: Conserved mammalian chemistry; human curated pathwaysEvidence boundary: These pathways describe the different jobs of B vitamins in normal metabolism. They do not establish benefits from giving extra vitamins to a cat whose diet already supplies enough.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4 · ↩ 5
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FEDIAF. Nutritional Guidelines for Complete and Complementary Pet Food for Cats and Dogs. Species/context: Cats and dogs; feline nutrition tables usedEvidence boundary: The feline tables guide the formulation of complete food. Their values describe the diet and its energy content, not an additional daily vitamin dose for an individual cat.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4 · ↩ 5 · ↩ 6 · ↩ 7
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Reactome. Metabolism of vitamin B2 (riboflavin). Species/context: Conserved mammalian chemistry; human curated pathwayEvidence boundary: Riboflavin supplies the material for FMN and FAD, cofactors involved in electron transfer. This explains a nutritional role without predicting an increase in activity after supplementation.↩ 1 · ↩ 2
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Reactome. Glutathione reductase regenerates reduced glutathione. Species/context: Conserved mammalian chemistry; human curated reactionEvidence boundary: Glutathione recycling uses NADPH and a flavin-dependent enzyme. The reaction helps explain why B-vitamin metabolism and antioxidant defence are connected.↩ 1 · ↩ 2 · ↩ 3
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S. C. Bai, D. A. Sampson, J. G. Morris, Q. R. Rogers. Vitamin B-6 requirement of growing kittens. Species/context: Growing kittensEvidence boundary: The researchers established B6 needs using controlled diets in growing kittens. The result supports adequate nutrition during growth, not a promise that extra B6 improves a well-fed adult cat’s coat or appetite.↩
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Chee-Hoon Chang, Jonathan Lidbury, Jan S. Suchodolski, Joerg M. Steiner. Effect of oral or subcutaneous administration of cyanocobalamin in hypocobalaminemic cats with chronic gastrointestinal disease or exocrine pancreatic insufficiency. Species/context: CatsEvidence boundary: Both oral and injected cyanocobalamin corrected low blood B12 in this trial. The cats had gastrointestinal disease or pancreatic insufficiency, and the study did not test a daily multinutrient formula.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4 · ↩ 5 · ↩ 6
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Ya-Pei Chang, Po-Yu Chiu, Chung-Tien Lin, I-Hsuan Liu, Chen-Hsuan Liu. Outbreak of thiamine deficiency in cats associated with the feeding of defective dry food. Species/context: CatsEvidence boundary: This report traced serious neurological illness in 17 cats to food with inadequate thiamine. It illustrates a deficiency emergency and does not establish that ordinary ageing or reduced play signals low B1.↩
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Jessica E. Markovich, Lisa M. Freeman, Cailin R. Heinze. Analysis of thiamine concentrations in commercial canned foods formulated for cats. Species/context: Commercial feline foods; laboratory composition analysisEvidence boundary: The study found low thiamine in some foods sampled at that time. It supports asking about nutritional quality control, but it cannot rank today’s brands or estimate the risk in a current bag or can.↩
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La Petite Labs. Hollywood Elixir official ingredient panel. Species/context: Cats and dogsEvidence boundary: The panel lists four B vitamins alongside NR, CoQ10 and glutathione per standard 2.5 g sachet. Hollywood Elixir is a daily multinutrient formula, not a complete B complex or a treatment for an identified deficiency.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4 · ↩ 5 · ↩ 6 · ↩ 7 · ↩ 8 · ↩ 9
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Rachel S. Fletcher, Joanna Ratajczak, Craig L. Doig, Lucy A. Oakey, Rebecca Callingham, Gabriella Da Silva Xavier, Antje Garten, Yasir S. Elhassan, Philip Redpath, Marie E. Migaud, Andrew Philp, Charles Brenner, Carles Canto, Gareth G. Lavery. Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells. Species/context: Mouse skeletal-muscle cells and miceEvidence boundary: This work traces NR metabolism into NAD+. It explains the precursor pathway, rather than demonstrating a clinical benefit from a multinutrient formula in cats.↩ 1 · ↩ 2
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Reactome. Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2. Species/context: Conserved mitochondrial pathway; human curated recordEvidence boundary: This pathway describes normal electron transfer in mitochondria. It explains the relationship between NADH and CoQ10, rather than the effects of taking a supplement.↩ 1 · ↩ 2
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Kayla Hyland, Rania Gollakner. Cyanocobalamin B12 or Cobalamin. Species/context: Dogs and catsEvidence boundary: This clinical handout covers administration, monitoring and possible reactions. The prescribed product and route determine the instructions.↩ 1 · ↩ 2
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F. Watanabe, H. Katsura, S. Takenaka, T. Fujita, K. Abe, Y. Tamura, T. Nakatsuka, Y. Nakano. Pseudovitamin B12 is the predominant cobamide of an algal health food, spirulina tablets. Species/context: Spirulina tablet composition; no animals supplementedEvidence boundary: This analysis distinguished vitamin B12 from a related analogue in spirulina tablets. It was a composition study, not a measurement of B12 absorption or deficiency treatment in cats.↩
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Cornell Feline Health Center. Feeding Your Cat. Species/context: CatsEvidence boundary: A complete diet appropriate to life stage provides the nutritional foundation. A vitamin product alone cannot balance an improvised diet or replace food.↩ 1 · ↩ 2 · ↩ 3
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La Petite Labs. Hollywood Elixir detailed ingredient list. Species/context: Cats and dogsEvidence boundary: The ingredient list identifies the B12 preparation and the forms of the other ingredients. A premix declaration should not be assumed to specify an equivalent amount of active vitamin for clinical treatment.↩ 1 · ↩ 2 · ↩ 3
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