The 12 Hallmarks of Aging in Dogs, Explained
Read full insightProtein for Senior Dogs: How Much, What Kind, and When to Be Careful
By La Petite Labs Editorial 20 min read
References
Numbered references identify the sources used for specific claims. Read the study design, species and evidence boundaries alongside each finding.
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Cornell University College of Veterinary Medicine. Choosing food for your senior dog. Evidence boundary: Cornell veterinary nutrition guidance on food choice, calories, muscle and appetite in senior dogs.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4
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Wakshlag JJ, Barr SC, Ordway GA, Kallfelz FA, Flaherty CE, Christensen BW, Shepard LA, Nydam DV, Davenport GM. Effect of dietary protein on lean body wasting in dogs: correlation between loss of lean mass and markers of proteasome-dependent proteolysis. Evidence boundary: A ten-week experiment in 56 young female dogs examining dietary protein composition and lean-body changes.↩ 1 · ↩ 2
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Sheffy BE, Williams AJ, Zimmer JF, Ryan GD. Nutrition and metabolism of the geriatric dog. Evidence boundary: A two-year study comparing nutrient use in older and young dogs fed four diets.↩
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Schauf S, Stockman J, Haydock R, Eyre R, Fortener L, Park JS, Bakke AM, Watson P. Healthy Ageing Is Associated with Preserved or Enhanced Nutrient and Mineral Apparent Digestibility in Dogs and Cats Fed Commercially Relevant Extruded Diets. Evidence boundary: Short feeding-period comparisons of apparent nutrient digestibility in healthy dogs and cats across ages.↩
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Varney JL, Adams HA, Fowler JW, Coon CN. PSVIII-B-10 Feeding Senior Labrador Retrievers Hydrolyzed Whey Protein Isolate to Prevent Sarcopenia. Evidence boundary: A conference report from a 26-week feeding project in 36 senior Labradors, including body-fat changes.↩ 1 · ↩ 2
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Coon CN, Timlin C, Fowler J, Mccracken F. PSX-8 Effect of Feeding Additional Whey Protein to Senior Labrador Retrievers for Maintaining Lean Mass and Minimizing Inflammation. Evidence boundary: A later conference report from the same 36-Labrador project, covering selected inflammatory and gait measurements.↩
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Li P, Wu G. Amino acid nutrition and metabolism in domestic cats and dogs. Evidence boundary: A review of amino-acid nutrition and metabolism in domestic cats and dogs.↩ 1 · ↩ 2
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U.S. Food and Drug Administration. “Complete and Balanced” Pet Food. Evidence boundary: FDA guidance on nutritional adequacy statements and dry-matter nutrient comparisons.↩ 1 · ↩ 2 · ↩ 3
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World Small Animal Veterinary Association. Global Nutrition Guidelines and Toolkit. Evidence boundary: Nutritional assessment resources, including body and muscle condition and food-selection questions.↩ 1 · ↩ 2 · ↩ 3 · ↩ 4
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International Renal Interest Society. IRIS Guidelines. Evidence boundary: The current IRIS framework for individual assessment and management of kidney disease.↩ 1 · ↩ 2
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Rachel S Fletcher, Joanna Ratajczak, Craig L Doig, Lucy A Oakey, Rebecca Callingham, Gabriella Da Silva Xavier, Antje Garten, Yasir S Elhassan, Philip Redpath, Marie E Migaud, Andrew Philp, Charles Brenner, Carles Canto, Gareth G Lavery. Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells. Evidence boundary: Mouse muscle-cell research describing NR metabolism and NAD+ synthesis.↩
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Reactome. Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2. Evidence boundary: A curated pathway describing mitochondrial electron transfer from NADH to CoQ.↩
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NIH Office of Dietary Supplements. Riboflavin: Fact Sheet for Health Professionals. Evidence boundary: NIH information on riboflavin and its FMN/FAD cofactor roles.↩
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Reactome. Detoxification of Reactive Oxygen Species. Evidence boundary: Curated pathways describing reactive-oxygen handling and glutathione-dependent reactions.↩
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La Petite Labs. Hollywood Elixir® Longevity System: serving and purchase options. Evidence boundary: Current manufacturer adult portions and directions for mixing with food.↩
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La Petite Labs. Publicly verified lab results and COA Lookup. Evidence boundary: Manufacturer information on facility standards, contaminant testing and batch-report access.↩
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