The 12 Hallmarks of Aging in Dogs, Explained
Read full insightWhen Is a Dog Considered an Adult
By La Petite Labs Editorial 15 min read
References
Numbered references identify the sources used for specific claims. Read the study design, species and evidence boundaries alongside each finding.
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Swanson KS, Kuzmuk KN, Schook LB, et al. Diet affects nutrient digestibility, hematology, and serum chemistry of senior and weanling dogs. Study design/context: not-stated-in-titleSpecies/context: dogEvidence boundary: The species/context tag is inferred only from the source title; the actual study population and claim-level relevance still depend on the full methods and outcomes.↩ 1 · ↩ 2 · ↩ 3
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Kang Y, Kim Y, Cho JH, et al. Age-related changes in growth and fecal parameters, nutrient digestibility, hematology, and serum biochemistry of Beagle dogs. Study design/context: not-stated-in-titleSpecies/context: dogEvidence boundary: The species/context tag is inferred only from the source title; the actual study population and claim-level relevance still depend on the full methods and outcomes.↩ 1 · ↩ 2 · ↩ 3
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German K, Melgoza C, Torres-Henderson C. Exploratory analysis of nutrient composition of adult and senior dog diets. Study design/context: not-stated-in-titleSpecies/context: dogEvidence boundary: The species/context tag is inferred only from the source title; the actual study population and claim-level relevance still depend on the full methods and outcomes.↩ 1 · ↩ 2 · ↩ 3
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Min Young Lee, Kyoung-Min So, Sang-Yeob Lee, et al. Comparative Evaluation of Nutrient Digestibility in Beagle Dogs of Different Life Stages. Study design/context: not-stated-in-titleSpecies/context: dogEvidence boundary: The species/context tag is inferred only from the source title; the actual study population and claim-level relevance still depend on the full methods and outcomes.↩ 1 · ↩ 2 · ↩ 3
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Ono A, Yoshizawa T, Matsumoto K. Evaluation of Necessity of 1-year Toxicity Study in Dogs - development of the New Tiered Approach for Toxicity Studies of Pesticide Considering Species Difference in "toxicity profile" and "toxicity dose-response". Study design/context: not-stated-in-titleSpecies/context: dogEvidence boundary: The species/context tag is inferred only from the source title; the actual study population and claim-level relevance still depend on the full methods and outcomes.↩
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Coleman AE, Creevy KE, Anderson R, et al. Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project. Study design/context: study protocol/design paperSpecies/context: dogEvidence boundary: The species/context tag is inferred only from the source title; the actual study population and claim-level relevance still depend on the full methods and outcomes.↩ 1 · ↩ 2 · ↩ 3
Further reading
These sources provide additional context but are not mapped to a numbered claim above.
- Bailey J, Thew M, Balls M. An analysis of the use of dogs in predicting human toxicology and drug safety.(2013).
- Parkinson C, Lumley CE, Walker SR. The value of information generated by long-term toxicity studies in the dog for the nonclinical safety assessment of pharmaceutical compounds.(1995).
- Dellarco VL, Rowland J, May B. A retrospective analysis of toxicity studies in dogs and impact on the chronic reference dose for conventional pesticide chemicals.(2010).
- Parkinson C, Grasso P. The use of the dog in toxicity tests on pharmaceutical compounds.(1993).
- Chitty KM, Chan B, Pulanco CL, et al. Discontinuities and disruptions in drug dosage guidelines for the paediatric population.(2018).
- Mansilla WD, Fortener L, Templeman JR, et al. Adult dogs of different breed sizes have similar threonine requirements as determined by the indicator amino acid oxidation technique.(2020).
- Rumbeiha W, Morrison J. A review of class I and class II pet food recalls involving chemical contaminants from 1996 to 2008.(2011).
- Kim HT, Loftus JP, Mann S, et al. Evaluation of Arsenic, Cadmium, Lead and Mercury Contamination in Over-the-Counter Available Dry Dog Foods With Different Animal Ingredients (Red Meat, Poultry, and Fish).(2018).
- Bilgiç B, Tarhan D, Ateş F, et al. Investigation of Trace and Macro Element Contents in Commercial Cat Foods.(2025).
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