LOY-002 vs Hollywood Elixir™: Drug vs Natural Longevity for Dogs

Pet owners everywhere are buzzing about LOY-002, the so-called “Loyal dog pill” under FDA review for canine life extension.

But is this new drug really the answer to healthy aging—or are there safer, holistic options like Hollywood Elixir™, a daily Loyal-style dog supplement built around natural cellular science?

Here’s a balanced comparison between LOY-002 for dogs and Hollywood Elixir™—the difference between a prescription drug and a transparent, multi-pathway longevity formula.

LOY 002 For Dogs

What Is LOY-002?

LOY-002 (also known as Loyal for Dogs) is an investigational prescription medication being developed to extend the healthy lifespan of senior dogs. It targets age-related metabolic decline, aiming to help older dogs stay active and sharp for longer.


Key facts:

  • Developed by Loyal, a biotech startup focused on longevity in companion animals. Intended for dogs aged 10+ years and over 14 lbs.

  • Currently in the STAY clinical trial, enrolling over 1,000 dogs. Projected launch: late 2025–2026, pending FDA conditional approval.

  • Expected price: “under $100/month,” according to Loyal’s CEO, Celine Halioua, though vet supervision and lab work add extra costs.

Loyal markets it as the first FDA-regulated dog life extension drug, offering pharmaceutical rigor rather than supplement-style wellness.

LOY 002 for dogs

Strengths and Promises

  • Regulatory oversight — Prescription-only model ensures veterinary monitoring.

  • Scientific ambition — One of the most comprehensive longevity trials in pet history.

  • Metabolic focus — Designed to slow insulin resistance and other metabolic aging pathways.

  • Potential impact — If results hold, it could extend healthy years for many senior dogs.

Where LOY-002 Falls Short

1. Limited Pathway Coverage

LOY-002 focuses narrowly on metabolism, missing broader pillars of aging like oxidative stress, mitochondrial decline, immune balance, and NAD+ depletion—all proven hallmarks of aging that require multi-layered intervention.

2. Prescription Friction

Every bottle will require vet approval, pre-screening bloodwork, and recurring exams—driving real-world costs well beyond the $100/month price tag.

3. No Option for Cats or Small Dogs

LOY-002 is dog-only—there is no LOY-002 for cats, and smaller breeds may not qualify for trials or prescriptions.


4. Data Still Maturing

LOY-002 is currently being studied in the large, multi-year STAY clinical trial, tracking over 1,000 senior dogs for long-term safety and efficacy. While this design is encouraging, the results are still years from publication—and until the drug has been used broadly outside controlled environments, real-world tolerability and interaction data remain limited.

“LOY-002 may one day extend lifespan — but it’s still a pharmaceutical experiment years from general use. Hollywood Elixir™ delivers daily, transparent longevity support that works across pathways today.”

hollywood elixir vet approved

Natural Alternative: Hollywood Elixir™

Hollywood Elixir™ by La Petite Labs takes a science-based but natural route to pet longevity.

Rather than one experimental pathway, it combines NAD+ precursors, antioxidants, adaptogens, and cofactors to strengthen multiple systems simultaneously—energy, immunity, and cellular defense. Ingredients are listed transparently and verified through NSF® third-party testing.

Unlike the Loyal dog supplement model, Hollywood Elixir™ requires no prescription, is safe for both dogs and cats, and delivers multi-pathway support now—without waiting years for FDA release.

leap years dog supplement compared to hollywood elixir

Why Hollywood Elixir™ Stands Out

  • Available today—no waiting for 2026 or FDA rollout.

  • Comprehensive—supports NAD+, antioxidants, and immune pathways together.

  • Transparent—each dosage listed and verified.

  • Multi-species—formulated for both dogs and cats.

  • Holistic longevity—reinforces vitality naturally, without prescription barriers.

FAQs About LOY-002 and Natural Longevity Support

What is LOY-002?

A prescription drug in development by Loyal to slow metabolic aging in senior dogs. It is still in clinical trials and projected for release in 2026.

How much will LOY-002 cost?

Loyal’s CEO says the goal is “under $100 per month,” but real costs including veterinary monitoring may be significantly higher.

Is LOY-002 safe?

It’s still under FDA review. Safety and long-term data are not yet available, so caution is warranted until results are published.

Is there a LOY-002 for cats?

No—LOY-002 is being developed only for dogs. For pet parents seeking safe, daily longevity support for both dogs and cats, Hollywood Elixir™ offers a research-driven, multi-pathway alternative.

What makes Hollywood Elixir™ different from LOY-002?

LOY-002 is a single-pathway pharmaceutical, while Hollywood Elixir™ supports multiple aging mechanisms naturally: NAD+, mitochondrial function, antioxidant defense, and immune balance.

When will LOY-002 be available?

Conditional FDA approval is expected in 2026 if trials succeed. Until then, it’s not available for public purchase.

Can dogs take both LOY-002 and Hollywood Elixir™ together?

That’s a question for a veterinarian once LOY-002 launches. For now, Hollywood Elixir™ provides a safe, comprehensive option without drug interactions or vet restrictions.

Mini Glossary

LOY-002

An investigational prescription drug developed by Loyal to slow metabolic aging in dogs. Currently in FDA-supervised clinical trials; not yet approved for sale.

NAD⁺ (Nicotinamide Adenine Dinucleotide)

A vital cellular coenzyme involved in energy metabolism and DNA repair that declines with age. Restoring NAD⁺ supports healthy aging in both pets and humans.

Metabolic Aging

Gradual cellular slowdown that reduces energy use and insulin sensitivity, contributing to age-related decline. LOY-002 aims to address this pathway directly.

Adaptogens

Natural compounds such as reishi and beta glucans that help the body adapt to stress and maintain immune balance — a key part of Hollywood Elixir’s approach.

Antioxidants

Molecules that neutralize oxidative stress from free radicals. Hollywood Elixir™ uses a network including glutathione, resveratrol, and astaxanthin to protect cells.

Multi-Pathway Support

A formulation philosophy targeting several biological aging mechanisms at once — energy, immunity, oxidative defense, and mitochondrial integrity — for broader protection than single-pathway drugs.