5 Coat Warning Signs of Illness in Dogs & Cats
Read full insightPeptides for Cats
15 science-backed barrier actives
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References
Numbered references identify the sources used for specific claims. Read the study design, species and evidence boundaries alongside each finding.
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Ricardo S. Vasconcellos, Josiane A. Volpato and Ingrid C. Silva. Bioactive peptides extracted from hydrolyzed animal byproducts for dogs and cats. Species/context: Dog and cat nutrition reviewEvidence boundary: Explains how processing and digestion break proteins into amino acids and peptides, and why the resulting mixtures differ by source and method.↩ 1 · ↩ 2 · ↩ 3
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Sherry Lynn Sanderson / Merck Veterinary Manual. Nutritional Requirements of Small Animals. Species/context: Cat and dog nutrition guidanceEvidence boundary: Describes feline nutrient requirements, protein quality and the importance of sufficient energy and an appropriate amino-acid supply.↩ 1 · ↩ 2
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Patrícia M. Oba and colleagues. Effects of diets supplemented with bioactive peptides on nutrient digestibility, immune cell responsiveness, and fecal characteristics, microbiota, and metabolites of adult cats. Species/context: 12 healthy adult cats; four 28-day diet periodsEvidence boundary: A feeding study compared complete diets containing chicken-liver or fish hydrolysates. The 4% fish diet improved dry-matter and organic-matter digestibility; the protein result was not statistically significant.↩
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Pamela Prestes Sezerotto and colleagues. Hydrolyzed chicken liver and increasing crude protein levels on palatability, digestibility, and intestinal fermentation products of cats. Species/context: Adult cats; separate digestibility and palatability experimentsEvidence boundary: Cats preferred diets containing the tested chicken-liver hydrolysate, while protein digestibility did not improve compared with poultry by-product meal. Preference and digestion were separate outcomes.↩
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Adjet Makawey, Christine Iben and Rupert Palme. Cats at the Vet: The Effect of Alpha-s1 Casozepin. Species/context: 60 owner-kept adult cats; veterinary-visit studyEvidence boundary: A particular casein-derived preparation was studied around veterinary visits. The authors reported fewer sweaty-paw responses, but no significant reduction in fecal cortisol metabolites.↩
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Shaohao Chen and colleagues. Effects of an antimicrobial peptide on transport- and novel environment-induced stress in British Shorthair cats. Species/context: 12 British Shorthair cats; 22-day controlled experimentEvidence boundary: A small study tested a yeast-derived antimicrobial-peptide preparation during transport and relocation. Selected stress and sleep measures improved; these results concern that preparation and setting.↩
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Erin D. Connolly and Guoyao Wu. Functions and Metabolism of Amino Acids in the Hair and Skin of Dogs and Cats. Species/context: Dog and cat physiology reviewEvidence boundary: Explains the different amino-acid composition of hair keratin and deeper skin proteins. It does not establish a supplement effect or regrowth timetable.↩
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S. Minami and colleagues. Clinical application of d-glucosamine and scale collagen peptide on canine and feline orthopedic diseases and spondylitis deformans. Species/context: 68 dogs and 3 cats; uncontrolled combined-intervention reportEvidence boundary: This uncontrolled report included three cats and 68 dogs receiving fish-scale collagen with glucosamine. It does not isolate a collagen effect or establish a feline serving.↩
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Canadian Academy of Veterinary Dermatology. Food Allergies and Elimination Diets in Cats. Species/context: Feline clinical guidanceEvidence boundary: Explains veterinary elimination diets, hidden food exposures and the need to contact the veterinary team promptly if a cat refuses the trial food.↩
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Cornell Feline Health Center. Feeding Your Cat. Species/context: Feline feeding guidanceEvidence boundary: Covers complete feline nutrition, food preferences and feeding environments. Food refusal and weight loss warrant veterinary assessment.↩
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Lei He and colleagues. Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs. Species/context: Rats and dogs; pharmacokinetic researchEvidence boundary: Includes injected BPC-157 pharmacokinetic research in beagles. It does not establish a feline treatment, an oral collagen effect or a home dosing regimen.↩
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La Petite Labs. Pet Gala Supplement Facts. Species/context: Manufacturer label for dogs and catsEvidence boundary: The label lists 500 mg marine collagen peptides and 250 mg hydrolyzed whey protein per 2.5 g sachet, alongside other skin-and-coat ingredients. Label composition is not an efficacy trial.↩ 1 · ↩ 2
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U.S. Food and Drug Administration. Proper Storage of Pet Food & Treats. Species/context: General pet-food guidanceEvidence boundary: Advises stopping a suspect food or treat and contacting a veterinarian when a pet becomes unwell, while retaining the product packaging and identifying information.↩
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Manuela Lefort-Holguin and colleagues. Efficacy and Safety of a Diet Enriched with EPA and DHA, Turmeric Extract and Hydrolysed Collagen in Management of Naturally Occurring Osteoarthritis in Cats: A Prospective, Randomised, Blinded, Placebo- and Time-Controlled Study. Species/context: Senior cats with osteoarthritisEvidence boundary: A controlled trial tested a complete diet containing omega-3s, turmeric and hydrolyzed collagen in cats with osteoarthritis. Improvements concern the combination, not collagen alone.↩
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M. L. MacDonald, Q. R. Rogers and J. G. Morris. Role of linoleate as an essential fatty acid for the cat independent of arachidonate synthesis. Species/context: Cats; feeding began at three months of ageEvidence boundary: An experimental deficient-diet study in cats established linoleate’s nutritional role in skin and coat condition and water retention. It did not test a commercial supplement or extra fat in an adequate diet.↩
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Yukiko Mizutani, Susumu Mitsutake, Kiyomi Tsuji, Akio Kihara and Yasuyuki Igarashi. Ceramide biosynthesis in keratinocyte and its role in skin function. Species/context: Mammalian epidermal biology reviewEvidence boundary: Reviews ceramides and the epidermal permeability barrier. It supplies biological background rather than a feline supplement trial.↩ 1 · ↩ 2
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