Disclosure: La Petite Labs publishes this review and sells pet supplements. Ark Naturals dental products are discussed for oral care; Hollywood Elixir is discussed separately for broader daily cellular nutrition. Hollywood Elixir does not replace brushing, dental chews or veterinary dental treatment.
Ark Naturals Pros and Cons
Ark Naturals is worth considering when you want a dental chew your dog will willingly take as part of regular oral care. Its range offers different textures and formulations, including the astaxanthin-containing Protection+ line. The useful starting point is the exact product, your dog’s mouth and the daily portion—not the brand name alone. 1 2
What makes it appealing
- A range centered on dental care, including firmer and softer options.
- A current Protection+ label that gives an astaxanthin amount, and a Joint Rescue panel with quantified ingredients.
- An established company whose facility audit and Quality Seal permission are confirmed by NASC. 4 12 13
What deserves attention
- Protection+ directions differ between the general brand blog and the specific Medium product listing.
- The brand’s reported dental percentages lack an accessible study report on its Clinical Results page.
- A chew’s taste or texture does not by itself demonstrate plaque or tartar reduction. Brushing and veterinary dental care remain central. 3 5 9
For an adult or senior dog, broader nutrition is a separate decision. Hollywood Elixir offers a full 17-active formula for cellular energy and healthy aging; its place alongside dental care is explained below.
Choose the exact chew before comparing the cost
Ark Naturals’ regular Brushless Toothpaste and Protection+ share a dental-care purpose, but they are different products. The brand describes the regular chew around its paste center and Protection+ around its added Asta-Shield antioxidant coating. Its range also includes Extreme Clean and softer formats. Match the size and texture to your dog rather than assuming every Ark chew is interchangeable. 2 3
For Protection+ Medium, 60 count, Chewy declares 2.6 mg astaxanthin per two chews, with two daily for dogs weighing 20–40 lb, aged 12 weeks and older. 4
There is a direction conflict to resolve: the brand’s August 2026 comparison article says one chew daily, while this specific listing and the Clinical Results page use two. Confirm the instructions on the current package with Ark Naturals before choosing the daily amount. 3 5
At two chews daily, the pack lasts 30 days: $49.99 one time, about $1.67 daily, or $47.49 on recurring Autoship. These October 2026 USD prices exclude tax, shipping and first-order promotions. 4
Check the package’s full ingredients and calories, especially for a restricted diet. The online inactive list ends mid-word, and current calories were not established.
What supports the Protection+ story?
Ark Naturals reports 15.2% less plaque and 78.4% less tartar, alongside a claim of greater effectiveness than a leading chew. Those are the manufacturer’s figures. The Clinical Results page does not provide the sample, methods, comparator or full report needed to assess them; its press-release link is a placeholder. Asking for the report is more useful than assuming either that the study is conclusive or that no study took place. 5
The ingredient explanation is easier to follow. Ark’s Asta-Shield article says astaxanthin was selected for its antioxidant role in gum-tissue support and explicitly separates that purpose from treating gum disease. It links two real papers. 6
Hussein and colleagues’ 2006 paper reviews astaxanthin biology and potential uses in human health. Naguib’s 2000 experiment measures antioxidant activity in laboratory media, including liposomal systems. Neither tested Protection+ in dogs or measured a dental-chew effect on plaque and tartar. 7 8
The papers help explain why an antioxidant ingredient was chosen. The clinical report would answer a different question: what the finished chew achieved, under which conditions. Keep those two useful questions separate when deciding whether the added coating is worth buying.
VOHC and NASC answer different questions
VOHC acceptance concerns a product’s plaque or tartar claim. The Veterinary Oral Health Council requires two trials with different animals. Its process also includes oral safety observations, a sponsor’s safety affidavit and reporting obligations. 11
Ark Naturals does not appear on the May 21, 2026 dog-product list reviewed for this article. That dated finding is not proof that its chews cannot help, nor a statement about every later update. If independently reviewed dental performance is the deciding factor, use the VOHC accepted-products directory to identify the exact product and claim. 10
NASC addresses a different part of the purchase: the company’s quality systems. NASC’s own Ark Naturals entry confirms an independent facility audit and permission to display its Quality Seal. That deserves credit. It does not amount to a clinical trial of each chew. 12
For a buyer, the distinction is simple: use dental evidence to assess a dental claim, and manufacturing information to understand how the company approaches quality.
The joint and digestive products have their own jobs
Dental care dominates Ark Naturals’ range, but it also lists Joint Rescue, Gentle Digest and Happy Traveler. Those products should be considered for their own purposes and labels. A dental-chew result cannot establish a joint, digestive or calming benefit. 2
The Joint Rescue Chicken soft chews, 9-oz bag provide a useful example of quantified labeling. Chewy lists the following per four soft chews: 13
| Declared ingredient | Per four soft chews |
|---|---|
| Glucosamine HCl | 500 mg |
| Chondroitin sulfate | 250 mg |
| Sea cucumber | 250 mg |
| MSM | 200 mg |
The listing gives 9 kcal per piece and weight-based directions. It also names ingredients such as chicken, cultured whey, fish oil and gelatin. These are not the amounts or preparation of the separate Super Strength tablet, and the panel does not prove a clinical joint outcome.
Bring the exact product to the veterinary discussion if your dog already receives joint care or follows a restricted diet. A brand can offer several useful formats without every product being right for the same dog.
Build a dental habit your dog can use
Acceptance matters. In one owner discussion about dental chews, a young husky stopped taking a familiar chew while the older dogs still enjoyed it. The owner wanted something that would fit the household’s established routine. That is one family’s practical question, not a survey or an efficacy test.
Choose a size and texture the dog can manage, supervise chewing and include the chew in the day’s food allowance. Ark’s own guidance recommends supervision and checking with a veterinarian for dental problems, missing teeth or individual dietary concerns. 3
Keep brushing in the plan. The AVMA identifies regular toothbrushing as the most effective home measure, with daily brushing best. Its guidance also recommends at least yearly veterinary dental checks; problems below the gumline can be missed by looking at the visible teeth. Persistent bad breath, bleeding, pain or changed eating needs assessment. 9
A chew is a daily addition to that care. Its role should be clear, its portion manageable and its use comfortable for the dog.
Manufacturing, recall history and the older score
Ark Naturals says its formulas are made in the USA. NASC records the company’s founding in 1996 and confirms its facility-audit status. These are more useful identity and quality facts than treating a missing name or document as proof that no expertise or testing exists. 1 12
The public material reviewed here did not establish a named formulation author for each product or a lot-specific laboratory report with a named lab. If those details affect your purchase, ask Ark for the formulator’s role and the report matching the exact product and lot. A report should say what was measured.
The 2023 recall belongs in its historical context
Thrive Market’s May 16, 2023 notice records a voluntary recall for potential mold involving specified Brushless Toothpaste value packs and best-by dates. Its Small and Medium listings were part of a larger manufacturer recall. Consult the original notice for the affected products; the event does not establish that every current Ark product is unsafe. 14
What the 49.5/100 score means
This review retains the 49.5/100 Public Transparency Score recorded on July 3, 2026, under the published rubric. It is not an effectiveness score, a safety score, or a best-brand ranking.
The number is historical, not a new score for the findings above. In particular, the current Protection+ amount is disclosed, and NASC’s company-audit confirmation should be credited. The Brand Transparency Report preserves that earlier scoring record.
A separate choice for cellular energy and healthy aging
Dental care protects one part of your dog’s health. If you also want daily nutrition for cellular energy and healthy aging, Hollywood Elixir brings that broader purpose to the meal. Its full 17-active NAD+ system combines precursor nutrients, mitochondrial cofactors, antioxidants and ingredients selected to support immune health. 15 21
How food becomes usable energy
Complete food supplies energy and essential nutrients. Cells then use a series of reactions to turn that fuel into usable energy. NAD carries electrons through this work; NR enters the pathways that replenish NAD. CoQ carries electrons within mitochondria, while riboflavin supplies FMN and FAD cofactors used by metabolic enzymes. 16 17 18 19
Hollywood Elixir puts NR tartrate, niacin, CoQ10 and B vitamins into the same formula as reduced glutathione and companion antioxidants. Vitamins C and E, astaxanthin, resveratrol, quercetin and blueberry contribute to its antioxidant design. Beta glucan, reishi and spirulina are selected for immune-support nutrition, with whey protein isolate completing the combination. You get the full combination for daily energy and healthy-aging nutrition, without choosing and measuring each ingredient separately. 15
The full 17-active formula
These are declared amounts per full 2.5 g sachet. Concentrations and preparation names remain part of the amount: a 2% astaxanthin preparation is not the same statement as pure astaxanthin. 15
| Declared ingredient or preparation | Per full sachet |
|---|---|
| Nicotinamide Riboside Tartrate | 60 mg |
| Coenzyme Q10 98% (Ubidecarenone) | 40 mg |
| L-Glutathione Reduced | 50 mg |
| Vitamin B3 (as Niacin) | 2 mg |
| Vitamin B2 (as Riboflavin), USP | 0.5 mg |
| Vitamin B6 (as Pyridoxal 5-Phosphate) | 1 mg |
| Vitamin B12 (as Methylcobalamin Trit 1% on DCP) | 0.25 mg |
| Vitamin C (as Ascorbic Acid) | 10 mg |
| Vitamin E, D-alpha Tocopheryl Acid Succinate 1210 | 15 IU |
| Astaxanthin 2% (natural) | 2 mg |
| Resveratrol Extract (Std. 98% from Polygonum Cuspidatum) | 15 mg |
| Quercetin Dihydrate 95% | 25 mg |
| Blueberry Fruit Powder | 50 mg |
| Beta Glucan (Beta-1,3/1,6-D-Glucan Powder), from Saccharomyces cerevisiae | 50 mg |
| Reishi Mushroom Powder P.E. (Std. 35% Polysaccharides) | 25 mg |
| Organic Spirulina Powder | 50 mg |
| Whey Protein Isolate 90% (WPI) | 250 mg |
The additional ingredients are chicken flavor, chicken liver powder, yeast extract, glycine and hydroxypropyl beta-cyclodextrin. The Hollywood Elixir ingredient guide gives the full declaration in context.
La Petite Labs describes manufacture in a US cGMP-compliant, NASC Preferred Supplier facility and third-party heavy-metal and microbial testing. Its COA Lookup provides a route to the available batch documents. Facility status and each report’s test scope are distinct from a clinical result. 20
These biological roles explain the formula’s nutritional purpose. They do not establish that Hollywood Elixir cleans teeth, treats gum disease or reproduces Protection+ study claims. Choose it for nutrition that supports cellular energy and healthy aging, while keeping dental care in place.
Choose the product for the care you want to add
For a dental chew, choose the exact Ark Naturals size and texture your dog can use. Resolve the Protection+ direction conflict, consider the recurring cost and decide how much weight you place on its coating and reported clinical results. If a VOHC-accepted product is your priority, use the current directory to choose one with the relevant claim.
For cellular energy and healthy-aging nutrition, choose Hollywood Elixir’s full 17-active NAD+ system. Its current daily portions are half a sachet under 7 lb, one at 7–30 lb and two over 30 lb. Use the portion that fits your adult dog’s weight and feeding plan. 21
Explore what Hollywood Elixir brings to daily care, then choose your dog’s Hollywood Elixir supply. The complete combination is already prepared for the meal; brushing, an appropriate dental product and veterinary care continue to serve their own roles.
Frequently asked questions
Is Ark Naturals legit?
Yes. NASC records its founding in 1996 and confirms an independent facility audit and Quality Seal permission. Assess the exact product for your dog; company identity and quality systems are different from clinical efficacy. 12
Is Ark Naturals clinically proven?
The brand reports dental percentages, but the reviewed Clinical Results page does not provide the complete report or methods behind them. Its placeholder press-release link does not resolve that question. Ask for the study if those figures determine your purchase. 5
What is in Protection+ dental chews?
Medium declares 2.6 mg astaxanthin per two chews. Check the package’s complete ingredients; the online inactive list is incomplete and other formulations differ. 4
Does Ark Naturals publish COAs or name a testing lab?
A public lot-specific report and named laboratory were not established in the materials reviewed. Ask for a report matching your product and lot. NASC independently confirms company-audit status; that does not identify every laboratory test. 12
Are Ark Naturals supplements well-labeled?
Some provide useful quantified panels. The Joint Rescue Chicken soft chew, for example, lists four ingredient amounts per four chews. Protection+ Medium also states an astaxanthin amount. Read the exact preparation and daily directions, rather than extending one label to the whole range. 4 13
Who formulates Ark Naturals products?
A named formulation author for each product was not established in this review. Ask Ark Naturals who developed the exact formula and what their role was. Not finding a name does not mean the company has no experts.
Where is Ark Naturals made?
Ark Naturals says its formulas are crafted in the USA. That is a country-of-manufacture statement, distinct from identifying or independently inspecting the current factory. 1
How much does Ark Naturals cost?
Protection+ Medium’s 60-count pack is $49.99 one time before tax and shipping. At two daily, it lasts 30 days; confirm the conflicting directions. 4
Do dental chews actually work?
Some products have evidence for reducing plaque or tartar. VOHC acceptance helps identify the specific product and claim. Do not assume every chew works equally, and keep brushing and veterinary assessment in the care plan. 9 11
Is there a La Petite Labs alternative to Ark Naturals?
Hollywood Elixir serves a different purpose: daily nutrition for cellular energy and healthy aging through its full 17-active NAD+ system. It can sit alongside an appropriate dental routine, but it does not replace brushing, dental chews or veterinary treatment. 15
What should I verify before buying Ark Naturals?
Confirm the exact product, size, complete ingredients, calories and package directions. For Protection+, resolve the one-versus-two-chew conflict. If the clinical percentages or testing influence your choice, request the report and relevant lot information. Have mouth pain, bleeding or changed eating assessed. 3 9
Sources
- Ark Naturals. About us. n.d.. Manufacturer description of the company’s dental range and USA manufacturing claim. ↩ ↩ ↩
- Ark Naturals. Products. n.d.. Current manufacturer catalog spanning dental care and other pet supplements. ↩ ↩ ↩
- Ark Naturals. Brushless Toothpaste vs. Protection+: which Ark Naturals dental chew is right for your dog. 2026. Manufacturer comparison of chew features, sizes and daily use, including the direction conflict discussed here. ↩ ↩ ↩ ↩ ↩
- Chewy. ARK NATURALS Brushless Toothpaste Protection+ Medium Dental Dog Treats, 60 count. n.d.. Retailer declaration for the Medium 60-count Protection+ product, with ingredient basis, directions and prices. ↩ ↩ ↩ ↩ ↩ ↩
- Ark Naturals. Clinical Results. n.d.. Manufacturer dental-result claims and the currently available supporting information. ↩ ↩ ↩ ↩
- Ark Naturals. Astaxanthin and your dog's mouth: the science behind Asta-Shield. 2026. Manufacturer explanation of astaxanthin’s intended role in its dental-chew design. ↩
- Hussein G, Sankawa U, Goto H, Matsumoto K, Watanabe H. Astaxanthin, a carotenoid with potential in human health and nutrition. 2006. DOI: 10.1021/np050354+. Review of astaxanthin biology and potential human-health applications. ↩
- Naguib YM. Antioxidant activities of astaxanthin and related carotenoids. 2000. DOI: 10.1021/jf991106k. Laboratory comparison of antioxidant activity in specified assay media. ↩
- American Veterinary Medical Association. Pet Dental Care. 2020. Veterinary guidance on home dental care, examinations and signs of dental problems. ↩ ↩ ↩ ↩
- Veterinary Oral Health Council. VOHC Accepted Products for Dogs — May 21, 2026. 2026. Dated official list of dog products accepted for specified plaque or tartar claims. ↩
- Veterinary Oral Health Council. Protocols & Submissions. n.d.. Official requirements for dental-claim trials, safety observations and reporting. ↩ ↩
- National Animal Supplement Council. Ark Naturals. n.d.. Primary NASC entry confirming company history, independent facility audit and Quality Seal permission. ↩ ↩ ↩ ↩ ↩
- Chewy. ARK NATURALS Joint Rescue Chicken Flavored Soft Chew Joint Supplement for Dogs, 9-oz bag. n.d.. Retailer ingredient and feeding information for the Chicken 9-oz Joint Rescue soft chews. ↩ ↩ ↩
- Thrive Market. May 16, 2023: Voluntary Recall of Antelope Ark Naturals Brushless Toothpaste, Due to Potential For Containing Mold. 2023. Original retailer notice identifying affected packs and dates within the 2023 potential-mold recall. ↩
- La Petite Labs. Hollywood Elixir®: current ingredient declaration. n.d.. Current manufacturer declaration of all 17 ingredient preparations and amounts per full sachet. ↩ ↩ ↩ ↩
- Sherry Lynn Sanderson. Nutritional Requirements of Small Animals. 2024. Veterinary overview of food energy, nutrients and their normal metabolic roles. ↩
- Rachel S Fletcher, Joanna Ratajczak, Craig L Doig, Lucy A Oakey, Rebecca Callingham, Gabriella Da Silva Xavier, Antje Garten, Yasir S Elhassan, Philip Redpath, Marie E Migaud, Andrew Philp, Charles Brenner, Carles Canto, Gareth G Lavery. Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells. 2017. DOI: 10.1016/j.molmet.2017.05.011. Mechanistic mouse and muscle-cell research explaining NR entry into NAD metabolism. ↩
- Reactome. Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2. n.d.. Curated molecular account of electron transfer from NADH to coenzyme Q. ↩
- NIH Office of Dietary Supplements. Riboflavin: Fact Sheet for Health Professionals. n.d.. Reference information on riboflavin-derived cofactors and normal energy metabolism. ↩
- La Petite Labs. Publicly verified lab results and COA Lookup. n.d.. Manufacturer quality information and the public route to available batch reports. ↩
- La Petite Labs. Hollywood Elixir Longevity System: current purpose and daily portions. 2026. Current manufacturer product purpose and weight-based daily portions. ↩ ↩